Nucleic Acid Extraction Kits From NextAdvance
*Tested on Bullet Blender Tissue Homogenizers with a wide variety of tissue samples*
Isolate nucleic acids (gDNA or Total RNA) from animal tissues using magnetic bead technology optimized for microfuge tubes.
In comparison with spin columns, magnetic beads offer a much faster and easier process. Yields and quality are as high or better and the process takes half the time.
The iron core beads are coated to bind nucleic acids. The beads travel in suspension in the homogenate, so the coated surfaces of the beads interact with the nucleic acids throughout the entire process. This allows the process time to be short and without high forces. Gentle inverting of the sample tubes a few times is sufficient.
In contrast, in spin columns, to have as much interaction between the nucleic acids and the coated fibers, the fibers must be so tightly woven together that the homogenate must be forced through the spin column under high pressure.
In summary, using magnetic beads is a faster, easier process and provides as good or better results.